Workflow from Scientific Research
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Regular nucleosome positioning surrounding NFRs is required and sufficient for chromatin domain formation. The strength of the domain boundaries depends on the width of the NFR, which is generated in vivo by a combination of regulatory proteins, including sequence-specific TFs (for example, Abf1 and Reb1) and ATP-dependent chromatin remodelers (for example, INO80, ISW2, Chd1 and RSC).
#Workflow#Illustration#Nucleosome Positioning#Chromatin Domain#NFR#Regulatory Proteins#Transcription Factors#Chromatin Remodelers
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