Scatter Plot from Scientific Research

Cytotoxic T-cell-mediated target cell lysis assays. Fraction of dead target cells after 24 h as a function of PTE concentration in the assay ( Supplementary Information ). Effector (PBMC) and target cell ratio was chosen as 5:1. Red dots, multispecific T-cell-engaging variant with anti-CD3 and at least two target-specific F(ab) fragments for the respective cell line. Black dots, monospecific controls. Solid lines, Hill fit to the data. Dashed line, PBMC and target cells without PTE after 24 h. Grey squares, blinatumomab-biosimiliar (Blina-BS). The error bars to the data are standard deviations to the mean of three biological replicates.

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