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T-cell activation was measured by using NFAT-luciferase Jurkat cell line in co-cultures with human ALL cell line NALM-6 in the presence of the indicated combinations. Relative T-cell activation (normalized to variants without target cell antibodies) of different variants for 100 pM and 1,000 pM DNA chassis concentrations. The icons in orange and blue indicate the respective antibodies used in the combination.
#Heatmap#T-cell Activation#NFAT-luciferase Jurkat Cell#ALL Cell Line#DNA Chassis Concentrations#Antibody Combinations
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