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Quantification of DyNAtrix-triggered immune response and haemocompatibility. Top: activation of monocytes in human whole blood was measured by flow cytometric quantification of CD11b expression. Bottom: platelet activation was assessed by quantification of the haemostasis marker platelet factor 4 (PF4). CCL-64-crosslinked 1% (w/v) P 5 and P 5 RGD were compared with 3 reference substrates: reactively cleaned glass, polytetrafluoroethylene (Teflon AF) and covalently crosslinked polyacrylamide (AA) gel. Data are shown as mean ± s.d. ( n = 3). Statistical analysis was performed using one-way ANOVA followed by a Holm–Sidak post hoc test (** P < 0.01).

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