Different DNA hydrogel designs give access to different concentration and stiffness regimes: comparison between previously reported synthetic DNA-crosslinked hydrogels (A, ref. 58 ; B, ref. 59 ; C, ref. 60 ; D, ref. 10 ; E, ref. 39 ; F, ref. 61 ; G, ref. 14 ) and several DyNAtrix gels (this study, red). DyNAtrix samples (1)–(6) were crosslinked with CCL-64 splints, while samples (7) and (8) had CCL-64 directly grafted onto the polymer backbone (compare Fig. 1c and Supplementary Fig. 10 ). (1) 1% (w/v) P 10 ; (2) 1.65% (w/v) P 5 ; (3) 1% (w/v) P 5 ; (4) 1% (w/v) P 1; (5) 0.2% (w/v) P 5 ; (6) 0.2% (w/v) P 1 ; (7) 1% (w/v) P 1,direct , (8) 0.2% (w/v) P 1,direct .
