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AUC of the ROC curve for each measure with the 10-year time window centered at EYO -10. Significant differences between the proteome and other measures were determined using a nonparametric permutation procedure as described in Methods. The resulting two-sided P values were not corrected for multiple comparisons. * P < 0.05, ** P < 0.01, *** P < 0.001. NS, not significant.
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