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Operational definition of sb-pQTLs: an SNP needs to meet both of the following two criteria to be declared a sb-pQTL. First, it is a pQTL in males or females or both at FDR < 0.05. Second, it has a significant genotype-by-sex interaction in protein expression at FDR < 0.05. We identified 166 index sb-pQTLs corresponding to 150 unique proteins in human brain.

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