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We also considered five cortical microstructural phenotypes: FA, MD, ICVF (also called neurite density index (NDI)), ISOVF and ODI. Each phenotype was measured globally (total or mean for the whole cortex) and regionally at each of 180 bilaterally averaged cortical regions defined by the Human Connectome Project parcellation scheme. We conducted genome-wide association studies of all phenotypes after removing outliers and investigated the latent structure of all phenotypes, developmental trajectories and cell type specificity and genetic organization.

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