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The R44X mutation in Rpe65 exon 3 in the rd12 mouse model and the optimized PE3b strategy used for correction of this mutation. The mutation (red), the epegRNA spacer (light blue) and the ngRNA spacer sequence (dark blue) are highlighted.
#Illustration#Table Image#R44X Mutation#Rpe65 Exon 3#rd12 Mouse Model#PE3b Strategy#epegRNA Spacer#ngRNA Spacer Sequence
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