Illustration from Scientific Research

Open access visualization of Illustration, Workflow, In-frame indels, ESM1b, Protein sequence
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DOI: 10.1038/s41588-023-01465-0

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Top: functional effect scores are assigned to in-frame indels by invoking ESM1b on both the WT and mutated protein sequence and calculating the PLLR between them. Bottom: the distribution of ESM1b effect scores over 1,679 benign and 1,791 pathogenic in-frame indels from ClinVar.

#Illustration#Workflow#In-frame indels#ESM1b#Protein sequence#ClinVar#Benign#Pathogenic

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