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Head-to-head comparison between ESM1b and each of the 18 other VEP methods over the same two dataset benchmarks (in terms of ROC-AUC). Because ESM1b provides scores for all missense mutations, the comparison against each other method is performed on the set of variants with effect predictions for that method. The percentage of variants considered for each method is shown at the bottom of each bar. IQR, interquartile range.
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