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HCT116 TRAIP-mAID cells were treated as in A but instead of DNA damage foci analysis, H2AX ChIP was conducted followed by RT-PCR to detect indicated TSS. N2 is a amplifying a fragment from gene desert on chromosome 13. Mean of n 3 with SEM. T.test per gene per condition: PH4B ctr vs IAA p = 0.034, WDR ctr vs IAA p = 0.018, WDR IAA vs IAA+Trip p = 0.016.
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