Scatter Plot from Scientific Research

Comparison of p values computed using FastKAST to an exact method. We analyzed Body mass index and Mean platelet volume (MPV) across 5000 unrelated white British individuals in the UK Biobank (UKBB). We tested each trait for nonlinear effects of SNPs in the UKBB genotyping array within non-overlapping 100 kb windows using the exact RBF kernel and FastKAST (with approximation dimension D = 50M where M is the number of SNPs in a tested window and the kernel hyperparameter γ = 0.1). p represents the p value computed using the exact kernel; represents the p value computed by FastKAST.

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