Protein Structure from Scientific Research

Structural models of PIEZO1, viewed extracellularly. The most complete cryo-EM structure of PIEZO1 with the missing distal approximately one third of the blade highlighted (left) and the AlphaFold II structure prediction of PIEZO1 (right) are shown. The C-terminal extracellular domain (CED) is removed from the AlphaFold II model due to poor prediction. TCO*K tags at position 103 are shown as magenta stars. Each protomer is separately coloured.

DOI