Bar Plot from Scientific Research

Confocal microscopy images of HEK293 cells co-expressing GFP–CaMKII F89G and mCherry-2BC in the presence of vehicle or 10 μM NM-PP1 before and after ionomycin stimulation. Correlation indices were measured before and after Ionomycin-induced colocalization of GFP–CaMKII (WT, K42M and F89G) with mCherry-2BC, represented as change in the correlation index (vehicle: n = 22, 17, 12 cells; NM-PP1: n = 20, 24, 13 cells; one-way ANOVA, Tukey’s multiple comparisons test). Scale bar, 10 μm. For vehicle, WT:F89G P < 0.0001, WT:K42M P < 0.0001 and F89G:K42M P = 0.7333. For NM-PP1, WT:F89G P = 0.7771, WT:K42M P = 0.0009 and F89G:K42M P < 0.0001. *** P < 0.001.

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