Left, representative epifluorescence images from three biologically independent experiments of Beas2B cells expressing YFP-tagged EML4-Alk v1, and treated with 1 M YB-0158 or DMSO for 1 h and immunostained for SAM68. Arrows indicate co-localization of EML4-Alk with SAM68 puncta. Right, co-localization analysis ( n = 3 biologically independent experiments per condition).
