Workflow from Scientific Research

Open access visualization of Workflow, Illustration, Ras-LOCKR-PL, TurboID, GTP-Ras
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DOI: 10.1038/s41587-023-02107-w

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Schematic of optimized Ras-LOCKR-PL consisting of split TurboID tethered to Cage and Key; GTP-Ras binds to RasBD, promoting reconstitution of functional TurboID and biotinylation of neighboring proteins. As in Fig. 1b, numbers correspond to regions that were optimzied during the development of Ras-LOCKR-PL.

#Workflow#Illustration#Ras-LOCKR-PL#TurboID#GTP-Ras#RasBD#Biotinylation

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