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Correlations between enhanced tyrosine sulfation and CKD-related atherosclerosis. Chronic kidney disease (CKD) is associated with increased levels of inorganic sulfate (SO 4 -2 ) and the consequently enhanced tyrosine sulfation, which leads to the increased sulfation of specific adhesion molecules and chemokine receptors, including CCR2 and CCR5. This contributes to monocytes/macrophages activation, finally favoring the process of CKD-related atherosclerosis

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