Illustration from Scientific Research

Alignment of target sites recombined by the RecFlex recombinase. Nucleotides of the half sites are highlighted in colors (adenine, blue; cytosine, red; guanine, green; thymine, yellow). Sequences of the spacers are shown in gray. A position probability matrix for the left and right half sites is shown to the right. A search using this matrix for potential therapeutic human genomic target sites revealed a candidate site on chromosome X (loxMECP2).

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