Illustration from Scientific Research

B Two 1 nt deletions between the reference genome and sequenced genome create the small seed m (top-left). m is assumed to be deleted by the occurrence filtering of our approach (top-right). This deletion leads to the replacement of the two correct entries a and b (bottom-left) with a wrong entry c (bottom-right). For salvaging such lost seeds, we rediscover m via a reseeding within the gray boxed area (top-right).

DOI