Illustration from Scientific Research

shows the dot-plot of A unfolded into the forward strand and reverse strand. There are two reads {r}_{1} and {r}_{2} , where {r}_{1} originates from the forward strand and {r}_{2} originates from the reverse strand of the sequenced genome. The locations of both reads on the sequenced genome (right) and the reference genome (top) are visualized, where the reads decompose into two segments on the reference genome. The reads indicate the inversion’s breakend pairs, once on the forward strand via the arrow labeled “a” and once on the reverse strand via the arrow labeled “b.”

DOI