Tumor/normal comparison of the COLO829 cell line using two different sequencing technologies: ONT MinION and PacBio Revio. Highlighted are the tumor-specific SVs (in red), the normal/control-specific SVs (in green) and the technology-specific SVs (dashed lines). In the cancer-specific SV, we found variants overlapping with cancer-related genes, such as PTEN, PMS2, ARHGEF5, PAK2 and WWOX. Differences between ONT and Revio calls for the same cell line can be attributed to either technology differences or the evolution of the cell line through time.
