FBP2 and FBP3 outperform the wild-type (WT) pathway when expressed in mammalian hosts. In experiments in mammalian cells, each gene was delivered on a separate plasmid. Experiments in mammalian cells at 37C. For mammalian cells, 100 M caffeic acid was used. Asterisk indicates samples where luminescence level was close to that of the background; for that reason, fold-change values are not provided. The boxes are the first and the third quartiles, whiskers are the rest of the distribution except outliers, and the orange line is the median. The difference between mean values and P values of post-hoc two-sided Conover test corrected by the step-down method using idak adjustments are indicated below the brackets between the box plots. KruskalWallis H test: H -statistic 33.07, P = 3.6 10 -6. N = 56 biologically independent samples.
