Bright-field and epifluorescence microscopy images of samples containing E. coli, nonresponsive (top) or responsive (bottom) particles and ciprofloxacin-loaded GUVs, recorded at t = 1440 min after sample preparation. Aggregation of DNA and the lack of GUVs in the sample with responsive particles indicates the successful rupture of vesicles following DNA-net formation. The released antibiotic hinders E. coli division, causing cell elongation. Particles (core motifs) are shown in red (Alexa Fluor 594), E. coli in cyan (EGFP). See FigureS16, Supporting Information for additional bright-field and epifluorescence microscopy images recorded at t = 0 and 1440 min.
