HP mice were significantly more mobile after lesion while mEC and control mice displayed no change in overall movement between pre- vs. post-lesion (control: 420.2 ± 24.1 min/day vs. 454.6 ± 31.6 min/day, t = -1.0067, p = 0.3435; HP: 385.5 ± 19.1 min/day vs. 685.3 ± 31.5 min/day, t = -6.7665, p = 0.0075; mEC: 445.1 ± 19.0 min/day vs. 498.6 ± 25.4 min/day, t = -1.1974, p = 0.3435). Pre-lesion period, blue; post-lesion period, orange. All data are represented as mean ± standard error of the mean (SEM). Independent-samples Student’s t test was used for all comparisons, unless stated otherwise. The normality of the data was verified with a Shapiro-Wilk test, and p values adjusted for false discovery rate with Benjamini-Hochberg correction. *p < 0.05, **p < 0.01, ***p < 0.005; n.s., not significant.
