Values are shown for patients with abnormal body temperature in 52 (1·6%) of 3214 patients in the care bundle and 68 (1·8%) of 3716 patients in the usual care group. Recordings were at 15-min intervals in the first hour after commencing treatment (time 0), hourly from hours 1 to 6, once every 6 h until 24 h, and twice per day until day 7. The overall means per treatment group and overall difference in variables between treatment groups at 1 h and at 24 h were calculated using a repeated-measure linear mixed model with a fixed effect of treatment, a fixed categorical effect of time, a fixed interaction between treatment and time, a repeated patient effect (to model within-patient correlations assuming a compound symmetry structure), and a random site effect, with adjustment for baseline measurements. R indicates time of random assignment.
00806-1%2Ffig2_d.webp&w=1920&q=75 "Learn How to Make Line Plot for Your Research Paper")