Histogram from Scientific Research

Comparison of accessibility distributions for four fragment screening datasets.2,17,18,19 Panels show the subset of cysteine residues liganded by two promiscuous scout electrophiles (dark blue, top panels) and covalent fragment/inhibitor libraries (red, bottom panels). Background distributions of non-liganded Cys are plotted for each study in gray. Inset shows number of unique cysteine residues plotted in each histogram.

DOI