Illustration from Scientific Research

Disulfide arrangement in the active and inactive forms of Ero1alpha. Description of disulfide bridges in the active form (Ox1) or the inactive form (Ox2) of Ero1alpha. Cysteine residues are shown as red (regulatory site), green (outer active site), or yellow (inner active site) dots with amino acid numbering, and disulfide bonds are depicted as green (shuttle disulfide bridge), yellow (inner active disulfide bridge), blue (reported regulatory disulfide bridge), or red (novel active disulfide bridge found in this study) lines.

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