Chemical Structure from Scientific Research

We note that while it was shown that Pierisin 1/2,15,40Scabin13and CARP-141link ADP-ribose to the N2 exocyclic amine of the guanine (as does ScARP and DarT1), our assumption that NADARs function as erasers of these modifications is only based on the fact that NADARs are hydrolytically active on N2-guanine-ADPr linkages and is not experimentally confirmed.

DOI