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Extracellular cytokine release of IFNγ (p = 0.0005), IL-2 (p = 0.0045), IL-4 (p = 0.0164), IL-10 (p = 0.0092), IL-17 (p = 0.0004), and IL-21 (p = 0.0037) by anti-CD3 (2 μg/mL), and anti-CD28 (20 μg/mL) activated Teff at 72 h activation IFNγ (p = 0.0410), IL-2 (p = 0.0056), IL-4 (p = 0.0277), IL-10 (p = 0.0044), IL-17 (p = 0.0005), and IL-21 (p = 0.0029). Data are representative of four independent experiments. Data are expressed as mean ± SEM. See alsoData S2.

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