WT and UBR5 -/- HEK293T cells were infected with VSV at a MOI of 0.5 for 8 h. Chromatin immunoprecipitation (ChIP) was performed with an anti-TRIM28 antibody. i The TRIM28-bound RLR promoter DNA was quantified by qPCR and normalized to its input. Bar: mean ± S.E.M, two-tailed Student’s t test, n = 4 biologically independent samples, *** p = 0.0006, ** p = 0.0094 for IFIH1 ; ** p = 0.0029; * p = 0.0382. Adjusted p values are presented.
