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Optogenetic control for light-induced activation of phosphoinositide 3-kinase (PI3K) via localized recruitment of inter SH2 domain (iSH2), resulting in Rac GTPase activation that initiates actin-driven cell protrusions (seeSTAR Methods).
#Workflow#Flowchart#Illustration#Optogenetics#Phosphoinositide 3-Kinase#PI3K#Rac GTPase#Actin#Cell Protrusions
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