Bar Plot from Scientific Research

Effects of MC3R mutations on -MSH-induced cAMP accumulation. Bars represent differences in the calculated -MSH potency (pEC 50 ) for representative mutants relative to the wild type (WT). Data are colored according to the extent of effect. Data shown are from at least three independent experiments performed in quadruplicate. All data were analyzed by one-way ANOVA and Dunnett’s test. * P < 0.05, ** P < 0.01, ***P < 0.001, and **** P < 0.0001. N.D. not determined.

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