Protein Structure from Scientific Research

The monomeric structures of BANAL-20-236 (magenta) (PDB ID: 8I3W) and BANAL-20-52 (blue) (PDB ID: 8HXJ) S proteins are superimposed to those of SARS-CoV-2 WH strain (PDB ID: 7XU6) (yellow) and Omicron BA.2.75 (PDB ID: 7YQW) (gray). The superimposed individual domain structures and the indicated loops (RBD (top left), NTD (top right), S2 (bottom left) and SD1 and SD2 (bottom right)) are also shown. Both SARS-CoV-2 and omicron BA.2.75 S proteins here are in down conformations at an acidic pH.

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