Chemical Structure from Scientific Research

Scheme for generating the Z Her2:342 -DOTA conjugate. Cartoon visualization of the Z Her2:342 Affibody based on crystal structures (PDB accession 3MZW ) 49 with the C-terminal splicease tag (in red, GG serves as a linker). In vivo splicing and subsequent in vitro conjugation to DOTA-tetrazine ( 7 ) yields conjugates for radiolabelling.

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