Additional speedups as a function of the resetting rate for MetaD simulations with bias deposition rate of 10 4 ns -1 (blue) or 20 ns -1 (green), for the two wells model. Full circles present results obtained from simulations, while dotted lines present estimations based on the first-passage time distribution with MetaD and no SR and using Equation ( 1 ). The dashed gray line indicates no additional speedup. Source data are provided as a Source Data file.