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Trial schema. Eligible patients were treated with two doses of neoadjuvant adebrelimab (20 mg per kg body weight, intravenously (IV), every 21 days (Q3W)), followed by surgical resection. Imaging studies were performed using radiological tools before and after immunotherapy. Tumor samples were collected at baseline and at the time of surgery. Longitudinal blood samples were collected at baseline, before dose 2, before surgery and within 4 weeks after surgery if available. D, day of therapy; R0, complete surgical resection.

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