Scatter Plot from Scientific Research

Healthy donor CD34 + HSPCs were electroporated with RNPs consisting of Cas9 complexed with sgRNA targeting the BCL11A erythroid enhancer. Percentage HbF versus percentage on-target edit. Gray highlighting indicates colonies with ≥87.5% editing efficiency (‘fully edited‘). Each dot represents an individual colony, and each color represents a different HSPC donor.

DOI