Intragenic means that SVs are fully included within genes. Gene-containing means SVs that contain at least one entire gene. Gene disruption corresponds to SVs having one breakpoint located within a gene and the other breakpoint in an intergenic region. Gene fusion indicates cases where the two SV breakpoints lie within two different coding sequences. In the essential column, n (no) and y (yes) mean not essential and essential genes, respectively. A manual review of 29 deleted genes, which are described as essential, revealed that they are in fact nonessential, are conditionally essential or are found deleted only at the heterozygous state.