Bar Plot from Scientific Research

Intragenic means that SVs are fully included within genes. Gene-containing means SVs that contain at least one entire gene. Gene disruption corresponds to SVs having one breakpoint located within a gene and the other breakpoint in an intergenic region. Gene fusion indicates cases where the two SV breakpoints lie within two different coding sequences. In the essential column, n (no) and y (yes) mean not essential and essential genes, respectively. A manual review of 29 deleted genes, which are described as essential, revealed that they are in fact nonessential, are conditionally essential or are found deleted only at the heterozygous state.

DOI