Microscopy from Scientific Research

Representative immunofluorescence images ( g ) of FANCD2 and MUS81 foci and scatterplot of FANCD2 foci ( h ) in MEL202 isogenic cells after 48 h DMSO or (50 nM) talazoparib exposure. Scale bar, 100 μm. Data are representative of n = 3 biological replicates, error bars show ±s.d. of individual nuclei assessed. P values are calculated by one-way ANOVA ( e , f and h ), **** P < 0.0001. NTC, nontargeting control; NS, not significant.

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