Box plots of resolving group A cytokines in resistant CC x K18-hACE2 mice (IL-6, IL-27, CCL2, CXCL10), or increasing group B cytokines in sensitive CC x K18-hACE2 mice (IL-10, CCL4). Box plots show data from individual mice (squares, circles, diamonds), the horizontal dashed lines represent the median value, the box indicates the first and third quartiles, and the whiskers indicate the maxima and minima values (Qlucore software). Source data are provided as a Source Data file. Two-tailed, unpaired Student’s t -test with Holm-Bonferroni multiple comparison posttest and 95% confidence interval were used to compare cytokine production in resistant versus sensitive strains (males and females combined). *p<0.05 was considered statistically significant.