D Trabecular and cortical bone of mice tibiae from B were analyzed and relative changes in % compared to PBS injections are shown for microarchitectural parameters: trabecular bone volume fraction (Tb. BV/TV), trabecular bone surface to bone volume ratio (Tb. BS/BV), D.T. trabecular number (Tb. N.), D.T. trabecular thickness (Tb. Th.), D.T. trabecular spacing (Tb. Sp.), cortical bone thickness (CT. Th.), average cross-sectional area of cortical bone (CT. BA/TA), and cortical tissue mineral density (CT. TMD). P d - 1 h w t Rag2 -/- 5TGM1 bearing tibiae n = 19; Pd-1h -/- Rag2 -/- 5TGM1 bearing tibiae n = 14. Mean ± SEM. * P ≤ 0.05, ** P ≤ 0.01 by two-tailed student’s t -test.
