Volcano Plot from Scientific Research

High-throughput screening of 8207 drug or drug candidates was performed to screen for ARIH1 enhancers that increase ARIH1 levels. After treatment with the drugs at 5 μM for 24 h, luciferase as a reporter to detect ARIH1 protein levels following exposing to the substrate (10 μM) in 384-well plates. Hit compounds are shown as red dots.

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