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Phylogenetic hypothesis obtained by maximum likelihood of cathepsin evolution of the major sponge lineages. The sequences obtained from the genome of O. minuta are shown in blue. Bootstrap values less than 70 are not shown. The list of sequences used and their accession numbers are available in Additional file 3 : Table S21, the alignment is provided at https://zenodo.org/communities/oops_13 [ 166 ]

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