Bar Plot from Scientific Research

Following recordings shown in B, oocytes were treated with the radiolabeled antibody 125I-mAb 295 to quantify the specific binding, i.e., the number of β2-containing nAChRs expressed in the plasma membrane (n = 3, 7 pooled oocytes each experiment). Cpm stands for counts per minute. α4:β2 RNA injection ratios favoring HS (1:7) and LS (7:1) stoichiometries are indicated on the X-axis. Data are presented as means ± SD and were analyzed using two-way ANOVA, followed by pairwise comparisons corrected for multiple comparisons with Holm-Šídák’s test. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001

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