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Schematic summary: CD206 + BMDM2- and BMDM2-derived TR-AM express Plet1 driving AEC II proliferation and upregulation of tight junction genes, ultimately resulting in AEC barrier repair. Application of exogenous, recombinant Plet1 reproduces these effects, highlighting its therapeutic potential. The figure was created with BioRender.
#Workflow#Flowchart#Illustration#Schematic#CD206#BMDM2#TR-AM#Plet1#AEC II#Proliferation#Tight Junction Genes#AEC Barrier Repair#Therapeutic Potential
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