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Schematic illustration of the potential influence of the arginine biosynthesis pathway in cutotypes 1 and 2 on natural moisturizing factors (NMFs) for skin hydration. Arginine biosynthesis played an important role in cutotype 1, but only a limited role in cutotype 2. The illustration was drawn based on the key correlations found between the dominant taxa, metabolic functions, and metabolites in the respective cutotypes. The KOs and metabolites highlighted by a rectangular box are those identified as having significant positive correlations in the network analysis

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