Plet1 concentration in supernatant of non-infected or infected AEC (24 h) ( n = 5); in supernatant of BALF-isolated TR-AM treated for 12 h with conditioned medium of non-infected ( n = 4) or infected AEC (12 h, n = 6, and 24 h, n = 5) or of untreated TR-AM ( n = 6) (*** p < 0.0001). Data are representative of three independent experiments shown as mean ± SEM statistical differences were calculated using one-way ANOVA and Tukey’s post-hoc tests. BMDM bone marrow-derived macrophage, AEC alveolar epithelial cell, BALF bronchoalveolar lavage fluid, TR-AM tissue-resident alveolar macrophage, D day. Source data are provided as a Source Data file.
