A Cytoscape network representation of the tricarboxylic acid (TCA) cycle, together with the breakdown of EC expression by taxon. MetaPro generates a Cytoscape compatible annotation file which can be used to map gene expression data onto KEGG defined pathways using the KEGGscape and enhancedGraphics plugin applications. Here, each node represents an individual enzyme with its size indicating the overall expression of that enzyme in the dataset (as defined by RPKM). Colored sectors indicate the contribution of each taxon to expression of that enzyme. To simplify the display, taxa were manually merged into 8 taxonomic groupings. Here, we see that members of Klebsiella and Citrobacter are the main contributors to the TCA cycle. These outputs were generated from a sample in the human oral biofilm dataset (SRR5984039).
