Manhattan Plot from Scientific Research

Manhattan plot showing -log 10 p -values testing for association between common (MAF > 0.01) genetic variants and time-to-first PN event using a Cox proportional hazards model for all patients (top) and for taxane-treated patients (bottom). SNPs reaching genome-wide significance are highlighted in red. Horizontal dashed line shows the genome-wide significance cutoff ( p < 5 x 10 -8 ). The GRID2 locus is indicated above.

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